Shanghai Hengdailao Trading Co., Ltd. is an enterprise specializing in the production and sales of biochemical reagents and scientific research reagents. The detailed performance and quality indicators of nalidixic acid produced by the company are as follows:
Chinese name: naphthyridone acid English name: Nalidixic acid
Other names: nalidixic acid, 1-ethyl-7-methyl-4-one-1,8-naphthyridine-3-carboxylic acid, 7-methyl-1-ethyl-4-oxo-1, 4-dihydro-1,8-naphthyridine-3-carboxylic acid, Nalidixic acid
CAS number: [389-08-2]
Molecular formula: C12H12N2O3
Molecular weight: 232.24
Shape: almost white or very light yellow powder. Odorless. Almost tasteless. Sensitive to light and air. Solubility at 23 ° C (mg / mL): chloroform 35, toluene 1.6, methanol 1.3, ethanol 0.9, water 0.1, ether 0.1. Dissolved in 350 parts of acetone at 20 ° C and slightly soluble in alkali hydroxide solution The lethal dose (mice, oral) was 3300 mg / kg.
Melting point: 229-230 ℃
Quality Standard:
Purity ≥99.0% (titration)
Solubility (2%; CHCl3) solution is transparent
Sulfated ash≤ 0.1%
Loss on drying ≤ 0.5%
Store at room temperature
The main applications are: inhibitors of bacterial DNA synthase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase.
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