Preparation of monoclonal antibody antigen
The antigen for preparing monoclonal antibodies must be an immune antigen, that is, any antigen that can cause an immune response. If it is not an immune antigen (also called a hapten), it will not stimulate the mice to produce antibodies. However, haptens that bind to macromolecular proteins (such as albumin) can also produce an immune response to T cells. Compared with the antigen used for preparing ordinary antiserum, the purity of the antigen used for monoclonal antibody preparation is the most important. When preparing monoclonal antibodies, the antigen should be purified as much as possible. The higher the purity of the antigen, the easier it is to obtain an excellent monoclonal antibody with strong specificity. Therefore, it is necessary to further introduce the knowledge of antigens related to the preparation of monoclonal antibodies.
Monoclonal antibodies can only recognize a single epitope, and polyclonal antibodies can recognize multiple epitopes on the same antigen. Studies have found that certain epitopes are more strongly immunogenic than others, and are immunodominant. Observation shows that an immune response of one epitope will weaken the response of another epitope, but when this dominant epitope is removed, the immune response of the originally damaged epitope will change from weak to strong.
The above article was collated and published by Shanghai Yanjin Biotechnology Co., Ltd. Shanghai Yanjin Biotechnology Co., Ltd. specializes in selling ELISA kits of various brands. Serving universities and immunology research units. Quality assurance and perfect after-sales service. And can be free to detect, better service for you.
Outdoor sofa is a kind of furniture for people to rest, relax and entertain in the outdoors. They are usually made of durable materials that can withstand the effects of various climatic conditions. The classification of outdoor sofas is mainly based on materials, design and function.
First, material classification:
1. Wooden outdoor sofa: This type of outdoor sofa is usually made of natural wood, such as teak. They are naturally beautiful and durable, suitable for outdoor Spaces such as gardens and terraces.
2. Metal outdoor sofa: This type of outdoor sofa is usually made of metal materials, such as iron, aluminum, etc. They have the characteristics of corrosion resistance, water resistance, sun protection, suitable for the beach, swimming pool and other humid environment.
3. Artificial materials outdoor sofa: This kind of outdoor sofa is usually made of artificial materials, such as plastic, artificial wood and so on. They have the characteristics of light, easy to clean, suitable for outdoor restaurants, cafes and other commercial places.
Ii. Design classification:
1. Single outdoor sofa: This kind of outdoor sofa is simple in design and suitable for single use. They are usually small and lightweight, suitable for small balconies, garden corners and other places where space is limited.
2. Double outdoor sofa: This kind of outdoor sofa is designed to be comfortable and suitable for two people. They are usually more spacious and suitable for placing in larger Spaces such as terraces and courtyards.
3. Multi-person outdoor sofa: This type of outdoor sofa is spacious and suitable for multi-person use. They often function as a sofa bed and can be used as a makeshift bed. Suitable for outdoor banquet area, holiday villa and other large outdoor space.
Iii. Functional classification:
1. Leisure outdoor sofa: This kind of outdoor sofa design is comfortable, suitable for people to relax in the outdoors. They are usually equipped with soft cushions and cushions to provide comfortable support.
2. Dining outdoor sofa: This type of outdoor sofa is designed for outdoor dining, such as open-air restaurants, cafes, etc. They are usually equipped with a dining table and chairs, providing a convenient dining experience.
Of course, a variety of different sofas can also be freely combined into a sofa combination to meet your different needs.
Rattan Sofa,Teak Sofa,Anti-Water Sofa,Sunscreen Sofa
Foshan Shengshi Zhihui Technology Co., Ltd. , https://www.szhfurniture.com