Jo-Ann M. Jablonski, Andrew J. Aubin, and Wendy Harrop
Waters Corporation (Milford, MA, USA)
Application Advantage
â– The Prep 150 LC system is a cost-effective and highly reliable preparative chromatography solution ideal for isolating compounds from natural product extracts. Its robust design ensures consistent performance, making it an excellent choice for labs looking to streamline their purification workflows.
â– Powered by ChromScopeâ„¢ software, the Prep 150 LC system offers an intuitive user interface that simplifies method development and compound purification. This ease of use reduces training time and enables users to focus more on results rather than setup.
â– With its straightforward operation and efficient sample processing capabilities, the Prep 150 LC system enhances lab productivity. It supports high-throughput applications and provides reliable separation of complex mixtures, ensuring reproducible outcomes in every run.
Waters Solutions
Prep 150 LC System
ChromScope Software
Atlantis® T3 Prep OBD Column
Atlantis T3 Analytical Column
Key Words
Separation, Purification, Preparative Chromatography, Prep 150 LC, Echinacea, Natural Product, Extract, ChromScope, Cichoric Acid
Introduction
Echinacea, commonly known as purple coneflower, is a hardy perennial plant belonging to the Asteraceae family. It thrives in dry climates and has been widely used in traditional medicine. One of the key bioactive compounds found in Echinacea is cichoric acid, a phenylpropanoid derivative with potential health benefits. Recent studies indicate that over 50% of published research on cichoric acid focuses on its therapeutic applications, including treatment of upper respiratory infections, immune modulation, and even cancer support. However, the concentration of cichoric acid can vary significantly depending on factors such as geographic origin, growing conditions, and sample preparation methods.
To conduct further research effectively, it is often necessary to isolate large quantities of the target compound. This requires multiple injections of crude extracts, which can be time-consuming and inefficient without the right tools. In this application note, we demonstrate how the Prep 150 LC system, combined with ChromScope software, can efficiently separate and purify cichoric acid from Echinacea extracts. The methodology described here is also applicable to other compounds that exhibit UV absorbance, making it a versatile approach for natural product isolation.
To view the full program, please click:
Separation of Natural Products from Echinacea Extract Using the Prep 150 LC System.doc
Bedroom Furniture ,Comfortable Design Beds,Drawers Bedside Tables,Stable Dressing Tables
INCHEE FURNITURE CO.,LTD , https://www.inchee.com